000			02191nam a2200265 4500
003			NALT
005			20251110115329.0
008			251106b th ||||| |||| 00| 0 eng d
040			_aNALT
050			_aRC 918.N45 _bN66C 2023
100	0		_aNoppanan Kotsaouppara. _966915
245	1	0	_aCharacterization of nephrotoxicity of damnacanthal in nude mice model / _cNoppanan Kotsaouppara.
260			_aBangkok : _bThammasat University, _c2023.
300			_a93 p. : _bill., tables, chart ; _c30 cm.
505	2		_aChapter 1 Introduction -- Chapter 2 Objectives -- Chapter 3 Review of literature -- 3.1 Nephrotoxicity -- 3.2 Nephrotoxicity induced by anthraquinone -- 3.3 Mechanisms of nephrotoxicity -- 3.4 The mouse grimace scale -- 3.5 General background of Damnacanthal -- Chapter 4 Materias and methods -- 4.1 Experimental outline -- 4.2 Preliminary experiment -- 4.3 Animal experiment -- 4.4 Blood chemistry evaluation -- 4.5 Gastrointestinal hemorrhage investigation -- 4.6 Urinalysis evaluation -- 4.7 Histopathology examination -- 4.8 Immunohistochemistry examination -- 4.9 Quantitative area percentage -- 4.10 Statistical analysis -- Chapter 5 Results -- 5.1 Monitoring of DAM20 and Veh treated nude mice during the study -- 5.2 Ultrasonic renal examination for physiology assessment -- 5.3 Urinalysis of DAM20 and Veh treated nude mice -- 5.4 Hematology and Blood chemistry evaluation of DAM20 and Veh treated nude mice -- 5.5 Histopathology examination of mice treated with high doses of damnacanthal -- 5.6 Histopathology examination of mice treated with repeated doses of DAM20 -- 5.7 Assessment of apoptosis and infiltrated macrophage subtype by immunohistochemistry in renal tissue of mice treated with damnacanthal -- Chapter 6 Discussion -- Chapter 7 Conclusion.
650		0	_aKidney _xdrug effects _966936
650		0	_aDamnacanthal _xToxicology _966937
650		0	_aKidney Diseases _xdrug therapy _966938
650		0	_aKidney diseases in animals _966939
942			_2lcc _cRSH
996			_ajidapa.t _bACQSTF _c2025-11-06
996			_avaree.k _bLIBSTF _c2025-11-07
996			_ajamriang.p _bCATSTF _c2025-11-10
999			_c107437 _d107437
998			_j1020 _k นางจำเรียง ระวังสำโรง